AMINOGUANIDINE
- Product Name
- AMINOGUANIDINE
- Chemical Name
- AMINOGUANIDINE
- Synonyms
- AMINOGUANIDINE;guanylhydrazine
- CBNumber
- CB3244221
- Molecular Formula
- CH6N4
- Formula Weight
- 74.09
- MOL File
- Mol file
AMINOGUANIDINE Chemical Properties,Usage,Production
Enzyme inhibitor
This substituted hydrazine (FWhydrochloride = 110.55 g/mol; CAS 79-17-4), also named pimagedine, is a strong inhibitor of diamine oxidases as well as nitric oxide synthase. Note that aminoguanidine also inhibits the formation of advanced glycosylation end-products, reportedly by reacting with and trapping Amadori rearrangement-derived fragmentation products in solution. In view of this property, aminoguanidine has often been used to treat complications associated with chronic diabetes. Target (s) : amine oxidase (copper-containing), or diamine oxidase; methylamine dehydrogenase; tryptophan tryptophylquinone enzymes ; nitric-oxide synthase; b-fructofuranosidase, or invertase; monoamine oxidase, or amine oxidase; histidine decarboxylase; aldose reductase; catalase; formation of advanced glycosylation end products; adenosylmethionine decarboxylase; arginine deaminase; arginine kinase; aspartate aminotransferase; histamine N-methyltransferase.